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In this exploration of our relationshop with the universe, the authors search for the grand design of the universe and the meaning of the so-called coincidences that allow life to exist on our planet. They present the latest advances in understanding of the nature of dark matter, explore mini and massive black holes, brown dwarfs and novel forms of matter such as quarks and quark nuggets. They discuss the search for a unified theory of all the particles and forces of nature: cosmic strings, superstrings and the possibility of a theory of everything. The authors also speculate on the possibility of the existence of other universes and of other intelligent life in our own.