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Breathless: The Scientific Race to Defeat a Deadly Virus

by David Quammen

MembersReviewsPopularityAverage ratingMentions
1765156,459 (4.02)8
Science. Nonfiction. HTML:National Book Award Finalist

The story of the worldwide scientific quest to decipher the coronavirus SARS-CoV-2, trace its source, and make possible the vaccines to fight the Covid-19 pandemic.
Breathless is the story of SARS-CoV-2 and its fierce journey through the human population, as seen by the scientists who study its origin, its ever-changing nature, and its capacity to kill us. David Quammen expertly shows how strange new viruses emerge from animals into humans as we disrupt wild ecosystems, and how those viruses adapt to their human hosts, sometimes causing global catastrophe. He explains why this coronavirus will probably be a "forever virus," destined to circulate among humans and bedevil us endlessly, in one variant form or another. As scientists labor to catch it, comprehend it, and control it, with their high-tech tools and methods, the virus finds ways of escape.

Based on interviews with nearly one hundred scientists, including leading virologists in China and around the world, Quammen explains that:
-Infectious disease experts saw this pandemic coming
-Some scientists, for more than two decades, warned that "the next big one" would be caused by a changeable new virusâ??very possibly a coronavirusâ??but such warnings were ignored for political or economic reasons
-The precise origins of this virus may not be known for years, but some clues are compelling, and some suppositions can be dismissed
-And much more.

Breathless takes you inside the frantic international effort to understand and control SARS-CoV-2 as if we were peering over the shoulders of the brilliant scientists who led the
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Showing 5 of 5
, ( )
  hazel1123 | Mar 19, 2024 |
Quammen interviewed many researchers involved in the Covid-19 pandemic during and just after the lockdown using Zoom. He has digested and presented this information for us in his usual straightforward and evenhanded way. The nature of RNA viruses, the known history of the progression of the pandemic, and various opinions on the origin of the virus are discussed. DQ occasionally goes off on a tangent, e.g. the details of Pangolin smuggling, but I found it all interesting. My edition from last year has an addendum that brings things up to date, although there hasn't been a lot of new data on the origin of the virus - the author explains why.
================================
There is a summary of the whole book at the end of the text that was largely made by abstracting what you've just finished reading. I found it unnecessary unless you aren't going to read the book.

Chapter 37, page 145: In addition, the CDC kept advising that, when local health departments could test they should focus only on people with a travel history, or people with severe symptoms... The author should explain why the CDC made this recommendation.

Chapter 69, page 279. a potluck banquet involving roughly forty thousand families [!] ( )
  markm2315 | Jan 28, 2024 |
An exhaustively researched presentation on the quest to find the beginnings of the COVID pandemic. The author leaves no stone unturned ultimately landing on four theories about its origin. Most of the book is written in a manner that a novice like me but I would be lying if I said I didn't get lost now and then in the detailed scientific data. Ultimately, I learned much and found the book valuable and should be read widely to insure an educated informed citizenry. ( )
  muddyboy | Mar 10, 2023 |
Among the many general-interest Covid books out there, Quammen successfully finds his own area. However, scientific research on Covid and its origins is broad enough that the book tends to be shallow and sometimes incoherent. The motivations of the research, and therefore of Quammen's discussions, aren't always spelled out. The book's timeliness also makes it inconclusive; there are still too many loose threads. The books on Covid vaccine development and deployment, written by active participants, have narrower focuses and much more rewarding conclusions. ( )
  breic | Nov 10, 2022 |
It's the first non-fiction book in English on the SARS-CoV-2 virus for the general public to include analyses of numerous science pre-prints which explain the scope and purpose of those writings. That makes Breathless essential reading for non-virologists who want to maintain an understanding of the current pandemic. Breathless has also just been published in the Italian language, with several other translations in the works. Included is a Notes/References section, where a list of sources for this book has been compiled. One website also used while writing Breathless is http://www.virological.org where virologists around the world provide early looks for their peers on current questions, data, and theories.

Breathless also makes the case for the continued global priority of doing whatever it takes to eliminate future spillovers of viruses, especially coronaviruses, that may otherwise continue to travel from Earth's ecosystems into our human populations.

Keep in mind that a book on the SARS-CoV-2 virus, written in the middle of that pandemic, is bound to leave a few loose ends. That's the purpose of research on these coronaviruses -- to keep expanding the boundaries of what we know. My hunch is that the COVID-19 pandemic will end someday, years from now. Thus, my family and I just bought another box of N95 masks.

PS: In November 2022, Breathless was included on the NYTimes list of the 100 best books of 2022. ( )
  MaureenRoy | Nov 1, 2022 |
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to all those who have lost loved ones in this pandemic
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To some people it wasn't surprising, the advent of this pandemic, merely shocking in the way a grim inevitability can shock.
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Science. Nonfiction. HTML:National Book Award Finalist

The story of the worldwide scientific quest to decipher the coronavirus SARS-CoV-2, trace its source, and make possible the vaccines to fight the Covid-19 pandemic.
Breathless is the story of SARS-CoV-2 and its fierce journey through the human population, as seen by the scientists who study its origin, its ever-changing nature, and its capacity to kill us. David Quammen expertly shows how strange new viruses emerge from animals into humans as we disrupt wild ecosystems, and how those viruses adapt to their human hosts, sometimes causing global catastrophe. He explains why this coronavirus will probably be a "forever virus," destined to circulate among humans and bedevil us endlessly, in one variant form or another. As scientists labor to catch it, comprehend it, and control it, with their high-tech tools and methods, the virus finds ways of escape.

Based on interviews with nearly one hundred scientists, including leading virologists in China and around the world, Quammen explains that:
-Infectious disease experts saw this pandemic coming
-Some scientists, for more than two decades, warned that "the next big one" would be caused by a changeable new virusâ??very possibly a coronavirusâ??but such warnings were ignored for political or economic reasons
-The precise origins of this virus may not be known for years, but some clues are compelling, and some suppositions can be dismissed
-And much more.

Breathless takes you inside the frantic international effort to understand and control SARS-CoV-2 as if we were peering over the shoulders of the brilliant scientists who led the

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